The grand scale and diversity of Montana’s geography and biological communities require science that spans many disciplines. Scientific knowledge guides where and how we work across a vast landscape, even as the land itself provides an invaluable outdoor laboratory for research. In the Northern Prairies, our Matador Ranch serves as a hub of research for grassland birds, wildlife-friendly fencing, and range management that sustains both the native prairie and its wildlife, and the family ranchers who have proven to be such reliable stewards and partners. On the Crown of the Continent, landowners have made changes in how they manage their property, guided by what science as learned are the needs of species such as grizzly bears and Canada lynx. There, as well as in Southwest Montana, ranchers are essential partners in combatting the spread on noxious weeds. Researchers studying wildlife as far ranging as bears and pronghorn, to pygmy rabbits and Arctic grayling have been supported by and collaborated with the Conservancy to ensure the long-term health and resilience of Montana’s intact natural systems.